3-(2-fluorophenyl)-1H-pyrazol-4-amine dihydrochloride
$300.00
CAS No.: 1788613-48-8
Catalog No.: 192871
Purity: 95%
MF: C9H10Cl2FN3
MW: 250.104
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.FC1=C(C=CC=C1)C1=NNC=C1N
Catalog No.: 192871
Purity: 95%
MF: C9H10Cl2FN3
MW: 250.104
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.FC1=C(C=CC=C1)C1=NNC=C1N
3-(2-fluorophenyl)-1H-pyrazol-4-amine dihydrochloride; CAS No.: 1788613-48-8; 3-(2-fluorophenyl)-1H-pyrazol-4-amine dihydrochloride. PROPERTIES: This compound presents as a white to off-white crystalline solid with molecular formula C10H9N3 {2HCl and a molecular weight of 245.16 g/mol. It exhibits a melting point in the range of 210-214 C and demonstrates good solubility in water and common polar solvents like methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 3-(2-fluorophenyl)-1H-pyrazol-4-amine dihydrochloride may cause respiratory irritation upon inhalation of dust. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 3-(2-fluorophenyl)-1H-pyrazol-4-amine dihydrochloride serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its fluorophenyl substituent enables improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrazole ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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