2-(piperidin-4-yloxy)pyrazine hydrochloride
$250.00
CAS No.: 1215636-48-8
Catalog No.: LT0001
Purity: 95%
MF: C9H14ClN3O
MW: 215.684
Storage: 2-8 degree Celsius
SMILES: Cl.N1CCC(CC1)OC1=NC=CN=C1
Catalog No.: LT0001
Purity: 95%
MF: C9H14ClN3O
MW: 215.684
Storage: 2-8 degree Celsius
SMILES: Cl.N1CCC(CC1)OC1=NC=CN=C1
CAS NO.: 1215636-48-8;2-(piperidin-4-yloxy)pyrazine hydrochloride. PROPERTIES: This piperidine pyrazine derivative salt appears as a white hygroscopic powder with a molecular weight of approximately 248.7 g/mol (free base). The 2-(piperidin-4-yloxy)pyrazine hydrochloride combines a piperidine ring with a pyrazine framework through an ether linkage. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 2-(piperidin-4-yloxy)pyrazine hydrochloride serves as a key intermediate in the synthesis of various pharmaceuticals. Its piperidine ring provides opportunities for alkylation and acylation reactions. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The pyrazine group undergoes reduction to form more complex ring systems. Additionally, it serves as a building block for creating kinase inhibitors with enhanced metabolic stability.
Reviews
Write Your Own Review