(Z)-ethyl 2-(dihydro-2H-pyran-3(4H)-ylidene)acetate
$450.00
CAS No.: 39858-68-9
Catalog No.: 192859
Purity: 95%
MF: C9H14O3
MW: 170.208
Storage: 2-8 degree Celsius
SMILES: O1C\C(\CCC1)=C/C(=O)OCC
Catalog No.: 192859
Purity: 95%
MF: C9H14O3
MW: 170.208
Storage: 2-8 degree Celsius
SMILES: O1C\C(\CCC1)=C/C(=O)OCC
(Z)-ethyl 2-(dihydro-2H-pyran-3(4H)-ylidene)acetate; CAS No.: 39858-68-9; (Z)-ethyl 2-(dihydro-2H-pyran-3(4H)-ylidene)acetate. PROPERTIES: This dihydropyran-substituted acetate ester has molecular formula C10H12O3. It appears as a white crystalline powder. The (Z)-ethyl 2-(dihydro-2H-pyran-3(4H)-ylidene)acetate demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 100-105 C, and it has a molecular weight of approximately 180.20 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may hydrolyze to the corresponding carboxylic acid upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The (Z)-ethyl 2-(dihydro-2H-pyran-3(4H)-ylidene)acetate serves as a valuable intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the dihydropyran ring provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The ylidene group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound functions as a building block in the preparation of liquid crystal materials with specific dielectric properties, useful in display technologies with response times below 20 milliseconds as described in materials chemistry journals. The ester group can be further functionalized through hydrolysis or amidation reactions to produce various derivatives for chemical research applications.
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