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(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one; CAS No.: 1383146-20-0; This dimethoxybenzyl piperazinone demonstrates our custom synthesis capabilities for opioid receptor modulation. The (R)-configuration and 2,4-dimethoxy groups enable -receptor selectivity. Our enzymatic amidation achieves stereochemical purity. The product enables development of peripheral opioid analgesics with reduced CNS side effects.