1-benzyl-2-phenylpiperazine
$350.00
CAS No.: 5368-33-2
Catalog No.: 192805
Purity: 95%
MF: C17H20N2
MW: 252.361
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1C(CNCC1)C1=CC=CC=C1
Catalog No.: 192805
Purity: 95%
MF: C17H20N2
MW: 252.361
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1C(CNCC1)C1=CC=CC=C1
1-benzyl-2-phenylpiperazine; CAS No.: 5368-33-2; 1-benzyl-2-phenylpiperazine. PROPERTIES: This benzyl- and phenyl-substituted piperazine has molecular formula C18H18N2. It appears as a pale yellow oil. The 1-benzyl-2-phenylpiperazine demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its boiling point ranges between 210-215 C at 760 mmHg, and it has a molecular weight of approximately 266.35 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive peroxides upon prolonged exposure to air. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 1-benzyl-2-phenylpiperazine serves as a valuable intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the piperazine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The benzyl and phenyl groups enhance metabolic stability by preventing oxidative degradation. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The amine groups can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
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