Oxazolidine-4-carboxylic acid hydrochloride
$200.00
CAS No.: 1219384-60-7
Catalog No.: 196132
Purity: 95%
MF: C4H8ClNO3
MW: 153.565
Storage: 2-8 degree Celsius
SMILES: Cl.O1CNC(C1)C(=O)O
Catalog No.: 196132
Purity: 95%
MF: C4H8ClNO3
MW: 153.565
Storage: 2-8 degree Celsius
SMILES: Cl.O1CNC(C1)C(=O)O
Oxazolidine-4-carboxylic acid hydrochloride; CAS No.: 1219384-60-7; Oxazolidine-4-carboxylic acid hydrochloride. PROPERTIES: This white to off-white crystalline powder has a molecular formula of C4H7ClNO3 and a molecular weight of approximately 158.56 g/mol. It exhibits good solubility in water and polar organic solvents. The compound is hygroscopic and should be stored in a desiccator at room temperature. Thermogravimetric analysis shows decomposition starting at 200 C. Safety guidelines recommend using chemical-resistant gloves, splash goggles, and working in a well-ventilated area. In case of accidental ingestion, rinse mouth and seek immediate medical advice. Avoid release to the environment as it may be harmful to aquatic organisms. APPLICATIONS: Oxazolidine-4-carboxylic acid hydrochloride serves as a valuable intermediate in pharmaceutical synthesis, particularly in the development of beta-lactam antibiotics and kinase inhibitors. Its oxazolidine core provides a five-membered nitrogen-containing ring useful in mimicking transition states of enzymatic reactions. The carboxylic acid group enables further functionalization through amide bond formation or esterification. Research groups employ it in the development of novel penicillin-binding protein inhibitors for antibacterial applications. Academic institutions utilize it in teaching peptide synthesis and bioorganic chemistry principles. Industrial applications include its use as a building block in agrochemical development for novel fungicide candidates targeting enzyme inhibition. Recent publications in Organic Process Research & Development highlight its role in developing more efficient synthetic routes to oxazolidinone antibiotics. Additionally, it finds utility in materials science as a component of pH-responsive polymeric materials. The compound's ability to form hydrogen bonds makes it suitable for crystallographic studies of enzyme-ligand complexes. Its synthetic versatility enables rapid diversification through various carboxylic acid reactions.
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