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(3-(2-chlorophenyl)isoxazol-5-yl)methanol; CAS No.: 438565-33-4; Specializing in Small molecules synthesis, we provide chlorophenyl isoxazole alcohols for COX-2 inhibition. The 5-hydroxymethyl group enables prodrug conjugation. Our 1,3-dipolar cycloaddition achieves regioselective isoxazole formation. This building block supports development of gastrointestinal-sparing NSAIDs through targeted isozyme inhibition.