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(3S,6R)-3-methyl-6-phenyl-1,2-thiazinane 1,1-dioxide
$792.00
CAS No.: 1537863-97-0
Catalog No.: 197295
Purity: 95%
MF: C11H15NO2S
MW: 225.313
Storage: 2-8 degree Celsius
SMILES: C[C@@H]1NS([C@H](CC1)C1=CC=CC=C1)(=O)=O
Catalog No.: 197295
Purity: 95%
MF: C11H15NO2S
MW: 225.313
Storage: 2-8 degree Celsius
SMILES: C[C@@H]1NS([C@H](CC1)C1=CC=CC=C1)(=O)=O
(3S,6R)-3-methyl-6-phenyl-1,2-thiazinane 1,1-dioxide; CAS No.: 1537863-97-0; (3S,6R)-3-methyl-6-phenyl-1,2-thiazinane 1,1-dioxide. PROPERTIES: This methyl-phenyl-substituted thiazinane dioxide features molecular formula C??H??N O? S with molecular weight 224.29 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 100-105 C. Exhibits IR absorption for sulfone (~1100-1000 cm??) and amine groups (~3300-3000 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a methyl-phenyl-substituted thiazinane dioxide, (3S,6R)-3-methyl-6-phenyl-1,2-thiazinane 1,1-dioxide is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the thiazinane dioxide group provides valuable conformational constraints for selective enzyme inhibition as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its sulfone functionality enables conjugation to biomolecules via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the thiazinane group contributes to improved flame retardancy and mechanical properties (Polymer International).
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