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2-methyl-1,3,4-oxadiazole; CAS No.: 3451-51-2; ChemShuttle offers 2-methyl-1,3,4-oxadiazole for bioisostere replacement strategies. This electron-deficient heterocycle serves as amide surrogate in medicinal chemistry. With molecular weight 84.08 and LogP 0.9, it improves metabolic stability while maintaining hydrogen bonding capacity. Our small molecule synthesis expertise ensures batch-to-batch consistency through controlled cyclization conditions. The methyl group enhances membrane permeability compared to unsubstituted oxadiazoles.