tert-butyl octahydro-2,7-naphthyridine-2(1H)-carboxylate
$650.00
CAS No.: 885270-18-8
Catalog No.: WLZ1235
Purity: 95%
MF: C13H24N2O2
MW: 240.347
Storage: 2-8 degree Celsius
SMILES: C1N(CCC2CCNCC12)C(=O)OC(C)(C)C
Catalog No.: WLZ1235
Purity: 95%
MF: C13H24N2O2
MW: 240.347
Storage: 2-8 degree Celsius
SMILES: C1N(CCC2CCNCC12)C(=O)OC(C)(C)C
CAS NO.: 885270-18-8; tert-butyl octahydro-2,7-naphthyridine-2(1H)-carboxylate. PROPERTIES: This protected heterocycle features a tert-butoxycarbonyl (Boc) group attached to an octahydro-2,7-naphthyridine framework, creating a molecule with potential applications in organic synthesis and medicinal chemistry. The tert-butyl octahydro-2,7-naphthyridine-2(1H)-carboxylate typically appears as a white to off-white crystalline solid with moderate solubility in common organic solvents. Its molecular structure includes a Boc protecting group that can be selectively removed under acidic conditions to release the amine functionality. For optimal stability and to prevent premature deprotection, this compound should be stored at 2-8 degree Celsius in a tightly sealed container under anhydrous conditions. When handling, chemists should wear appropriate personal protective equipment including nitrile gloves and safety goggles. This compound is sensitive to moisture and may hydrolyze in aqueous environments. In case of accidental ingestion, rinse mouth thoroughly and seek immediate medical attention. APPLICATIONS: The tert-butyl octahydro-2,7-naphthyridine-2(1H)-carboxylate serves as a valuable intermediate in the synthesis of pharmaceuticals, particularly those targeting the central nervous system. The naphthyridine scaffold provides a platform for developing receptor modulators with specific binding profiles. In medicinal chemistry, this compound functions as a building block for creating antipsychotic and anxiolytic agents where the heterocyclic core contributes to target engagement. Additionally, the molecule finds utility in chemical biology studies where its protected amine functionality can be selectively revealed for further conjugation. Researchers utilizing this compound benefit from its functional group compatibility, enabling the development of therapeutic agents targeting various disease pathways including neuropsychiatric conditions.
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