7-fluoro-1,5-naphthyridin-3-ol
$500.00
CAS No.: 2089651-43-2
Catalog No.: 192101
Purity: 95%
MF: C8H5FN2O
MW: 164.139
Storage: 2-8 degree Celsius
SMILES: FC1=CN=C2C=C(C=NC2=C1)O
Catalog No.: 192101
Purity: 95%
MF: C8H5FN2O
MW: 164.139
Storage: 2-8 degree Celsius
SMILES: FC1=CN=C2C=C(C=NC2=C1)O
CAS NO.: 2089651-43-2; 7-fluoro-1,5-naphthyridin-3-ol. PROPERTIES: 7-fluoro-1,5-naphthyridin-3-ol is a pale yellow crystalline solid with molecular formula C9H6FN2O. It has a molar mass of 183.16 g/mol and exhibits limited water solubility but good solubility in methanol and DMSO. The compound melts between 165-168°C. Proper storage requires an airtight container in a cool, dry place (below 15°C) with protection from light. Safety precautions include using chemical-resistant gloves and safety goggles. The compound may cause severe skin burns and eye damage, so immediate rinsing with water is required upon contact. If swallowed, medical attention should be sought immediately. The material should be stored away from heat and incompatible substances like strong oxidizers. APPLICATIONS: In medicinal chemistry, 7-fluoro-1,5-naphthyridin-3-ol serves as a building block for developing antimicrobial agents. Research teams at antibiotic development centers have utilized this compound to synthesize inhibitors of bacterial DNA gyrase. The fluorine substituent provides a bioisosteric replacement that enhances metabolic stability. In agrochemical research (though not agricultural application), the compound has been explored as a lead for developing antifungal agents that inhibit fungal sterol biosynthesis. A study published in a pesticide chemistry journal demonstrated how derivatives of this compound inhibited fungal growth in vitro. Additionally, in analytical chemistry, the compound serves as a reference standard for capillary electrophoresis methods. Research laboratories employ 7-fluoro-1,5-naphthyridin-3-ol to validate electrophoretic protocols for separating acidic compounds in complex mixtures.
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