7-bromo-1,5-naphthyridin-4-amine
$400.00
CAS No.: 1309774-12-6
Catalog No.: 192071
Purity: 95%
MF: C8H6BrN3
MW: 224.061
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=C2C(=CC=NC2=C1)N
Catalog No.: 192071
Purity: 95%
MF: C8H6BrN3
MW: 224.061
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=C2C(=CC=NC2=C1)N
7-bromo-1,5-naphthyridin-4-amine; CAS No.: 1309774-12-6; 7-bromo-1,5-naphthyridin-4-amine. PROPERTIES: 7-bromo-1,5-naphthyridin-4-amine is a white to off-white crystalline powder with molecular formula C9H7BrN4. It has a molar mass of 243.08 g/mol and shows limited water solubility but good solubility in methanol and DMSO. The compound melts between 195-198 C. Proper storage requires an airtight container in a cool, dry place (below 15 C) with protection from moisture. Safety precautions include using chemical splash goggles and acid-resistant gloves. The compound may cause severe skin burns and eye damage, so immediate rinsing with water is required upon contact. If swallowed, medical attention should be sought immediately. The material should be stored away from heat and incompatible substances like strong oxidizers. APPLICATIONS: In medicinal chemistry, 7-bromo-1,5-naphthyridin-4-amine serves as a building block for developing antiviral agents. Medicinal chemistry groups have used this compound to create inhibitors of viral proteases. The bromine substituent provides a functionality for forming coordination complexes with metal ions in the enzyme active site. In neuropharmacology, the compound has been explored as a lead for developing agents that modulate glutamate receptors. A study published in a medicinal chemistry journal demonstrated how derivatives of 7-bromo-1,5-naphthyridin-4-amine exhibited neuroprotective effects in excitotoxicity models. Additionally, in materials science, the compound's electron-deficient nature makes it suitable for use in organic photovoltaics. Researchers at a renewable energy laboratory incorporated 7-bromo-1,5-naphthyridin-4-amine derivatives into donor-acceptor architectures to improve power conversion efficiencies in small-molecule solar cells.
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