2-methyl-4-morpholinobutan-2-amine hydrochloride
$225.00
CAS No.: 2044927-06-0
Catalog No.: 192752
Purity: 95%
MF: C9H21ClN2O
MW: 208.733
Storage: 2-8 degree Celsius
SMILES: Cl.CC(C)(CCN1CCOCC1)N
Catalog No.: 192752
Purity: 95%
MF: C9H21ClN2O
MW: 208.733
Storage: 2-8 degree Celsius
SMILES: Cl.CC(C)(CCN1CCOCC1)N
2-methyl-4-morpholinobutan-2-amine hydrochloride; CAS No.: 2044927-06-0; 2-methyl-4-morpholinobutan-2-amine hydrochloride. PROPERTIES: This methylated morpholinobutane amine salt has molecular formula C8H19N2O {HCl. It typically appears as a white crystalline powder. The 2-methyl-4-morpholinobutan-2-amine hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 150-155 C (with decomposition), and it has a molecular weight of approximately 187.69 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 2-methyl-4-morpholinobutan-2-amine hydrochloride functions as a key intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the morpholine group provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The amine group forms additional hydrogen bonds with receptor residues. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the amine group reacts with targeting moieties, as described in pharmaceutical sciences journals. The amine group can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
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