(R)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride
$600.00
CAS No.: 2703745-93-9
Catalog No.: 192737
Purity: 95%
MF: C11H14ClNO3
MW: 243.69
Storage: 2-8 degree Celsius
SMILES: Cl.COC=1C=C2CCN[C@H](C2=CC1)C(=O)O
Catalog No.: 192737
Purity: 95%
MF: C11H14ClNO3
MW: 243.69
Storage: 2-8 degree Celsius
SMILES: Cl.COC=1C=C2CCN[C@H](C2=CC1)C(=O)O
(R)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride; CAS No.: 2703745-93-9; (R)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride. PROPERTIES: This methoxy-substituted tetrahydroisoquinoline carboxylic acid salt has molecular formula C10H13N2O2 {HCl. It typically appears as a white crystalline powder. The (R)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 200-205 C (with decomposition), and it has a molecular weight of approximately 227.69 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (R)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride functions as a valuable intermediate in the synthesis of adenosine receptor antagonists for cardiovascular indications where the methoxy group provides essential lipophilicity for receptor binding (as reported in medicinal chemistry literature). The carboxylic acid group forms ionic interactions with receptor residues. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the carboxylic acid group reacts with amino groups on targeting moieties, as described in pharmaceutical sciences journals. The carboxylic acid can be further functionalized through esterification or amidation reactions to produce various derivatives for chemical research applications.
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