8-hydroxyisoquinoline-6-carboxylic acid
$500.00
CAS No.: 1556953-43-5
Catalog No.: 192374
Purity: 95%
MF: C10H7NO3
MW: 189.17
Storage: 2-8 degree Celsius
SMILES: OC=1C=C(C=C2C=CN=CC12)C(=O)O
Catalog No.: 192374
Purity: 95%
MF: C10H7NO3
MW: 189.17
Storage: 2-8 degree Celsius
SMILES: OC=1C=C(C=C2C=CN=CC12)C(=O)O
8-hydroxyisoquinoline-6-carboxylic acid; CAS No.: 1556953-43-5; 8-hydroxyisoquinoline-6-carboxylic acid. PROPERTIES: 8-hydroxyisoquinoline-6-carboxylic acid is a crystalline compound with molecular formula C9H6N2O3. It has a melting point between 230-235 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This hydroxylated isoquinoline carboxylic acid is used in the development of anticancer prodrugs. The hydroxyl group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 8-hydroxyisoquinoline-6-carboxylic acid serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the carboxylic acid group enables photoinduced cross-linking with target proteins.
Reviews
Write Your Own Review