8-bromo-7-methoxyisoquinoline
$400.00
CAS No.: 67335-10-8
Catalog No.: 192357
Purity: 95%
MF: C10H8BrNO
MW: 238.084
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=CC=C2C=CN=CC12)OC
Catalog No.: 192357
Purity: 95%
MF: C10H8BrNO
MW: 238.084
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=CC=C2C=CN=CC12)OC
8-bromo-7-methoxyisoquinoline; CAS No.: 67335-10-8; 8-bromo-7-methoxyisoquinoline. PROPERTIES: 8-bromo-7-methoxyisoquinoline is a crystalline substance with molecular formula C10H7BrNO. It has a melting point of approximately 145-150 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, methoxy-substituted isoquinoline is used in the development of anticancer prodrugs. The bromine substituent serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 8-bromo-7-methoxyisoquinoline serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
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