7-bromoisoquinolin-5-ol
$500.00
CAS No.: 2703756-68-5
Catalog No.: 192359
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C=2C=CN=CC2C1)O
Catalog No.: 192359
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C=2C=CN=CC2C1)O
7-bromoisoquinolin-5-ol; CAS No.: 2703756-68-5; 7-bromoisoquinolin-5-ol. PROPERTIES: 7-bromoisoquinolin-5-ol is a crystalline powder with molecular formula C9H5BrNO2. It has a melting point of approximately 170-175 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding contact with eyes and skin due to its potential to cause serious eye damage and skin irritation. APPLICATIONS: This brominated quinoline alcohol is employed in the development of dual kinase/HDAC inhibitors. The amine group facilitates binding to the catalytic site of kinases while the bromine substituent enhances HDAC inhibitory activity as described in cancer research literature. In chemical biology, 7-bromoisoquinolin-5-ol serves as a tag for bioorthogonal labeling. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables conjugation with azide-containing biomolecules via click chemistry.
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