5-bromoisoquinolin-6-ol
$450.00
CAS No.: 918488-42-3
Catalog No.: 192341
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC1=C2C=CN=CC2=CC=C1O
Catalog No.: 192341
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC1=C2C=CN=CC2=CC=C1O
5-bromoisoquinolin-6-ol; CAS No.: 918488-42-3; 5-bromoisoquinolin-6-ol. PROPERTIES: 5-bromoisoquinolin-6-ol is a crystalline substance with molecular formula C9H5BrNO2. It has a melting point of approximately 160-165 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated isoquinoline alcohol is used in the development of anticancer prodrugs. The hydroxyl group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 5-bromoisoquinolin-6-ol serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
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