4-bromoisoquinolin-6-amine
$450.00
CAS No.: 2013582-86-8
Catalog No.: 192269
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=CC=C(C=C12)N
Catalog No.: 192269
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=CC=C(C=C12)N
4-bromoisoquinolin-6-amine; CAS No.: 2013582-86-8; 4-bromoisoquinolin-6-amine. PROPERTIES: 4-bromoisoquinolin-6-amine is a crystalline substance with molecular formula C9H6BrN3. It has a melting point of approximately 160-165 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated isoquinoline amine is used in the development of anticancer prodrugs. The bromine substituent serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 4-bromoisoquinolin-6-amine serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
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