4-bromo-8-nitroisoquinoline
$350.00
CAS No.: 677702-62-4
Catalog No.: 192215
Purity: 95%
MF: C9H5BrN2O2
MW: 253.055
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=C(C=CC=C12)[N+](=O)[O-]
Catalog No.: 192215
Purity: 95%
MF: C9H5BrN2O2
MW: 253.055
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=C(C=CC=C12)[N+](=O)[O-]
4-bromo-8-nitroisoquinoline; CAS No.: 677702-62-4; 4-bromo-8-nitroisoquinoline. PROPERTIES: 4-bromo-8-nitroisoquinoline is a crystalline substance with molecular formula C9H5BrN2O2. It has a melting point of approximately 145-150 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, nitro-substituted isoquinoline is used in the development of anticancer prodrugs. The nitro group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 4-bromo-8-nitroisoquinoline serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the nitro group enables photoinduced cross-linking with target proteins.
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