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1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid hydrochloride; CAS No.: 1203579-50-3; ChemShuttle provides 1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid hydrochloride, a key intermediate for opioid receptor modulators. Operating as custom synthesis companies, we optimize salt forms for enhanced bioavailability in CNS drug candidates. The tetrahydroisoquinoline scaffold s conformational restriction improves target binding affinity, while the carboxylic acid enables prodrug derivatization. Our services include polymorph screening and salt selection to address formulation challenges in late-stage development.