2-(2,6-dioxopiperidin-3-yl)-4-(piperazin-1-yl)isoindoline-1,3-dione
$350.00
CAS No.: 2230956-83-7
Catalog No.: 197725
Purity: 95%
MF: C17H18N4O4
MW: 342.355
Storage: 2-8 degree Celsius
SMILES: O=C1NC(CCC1N1C(C2=CC=CC(=C2C1=O)N1CCNCC1)=O)=O
Catalog No.: 197725
Purity: 95%
MF: C17H18N4O4
MW: 342.355
Storage: 2-8 degree Celsius
SMILES: O=C1NC(CCC1N1C(C2=CC=CC(=C2C1=O)N1CCNCC1)=O)=O
2-(2,6-dioxopiperidin-3-yl)-4-(piperazin-1-yl)isoindoline-1,3-dione; CAS No.: 2230956-83-7;2-(2,6-dioxopiperidin-3-yl)-4-(piperazin-1-yl)isoindoline-1,3-dione. PROPERTIES: 2-(2,6-dioxopiperidin-3-yl)-4-(piperazin-1-yl)isoindoline-1,3-dione is a substituted isoindoline derivative with a molecular weight of 403.41 g/mol. This white crystalline solid has a melting point between 210-213 C. The molecule features an isoindoline-1,3-dione ring substituted at position 2 with a 2,6-dioxopiperidin-3-yl group and at position 4 with a piperazin-1-yl group. It demonstrates limited solubility in common organic solvents such as ethyl acetate and methanol but is sparingly soluble in water. Proper storage involves keeping in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the dione groups' potential to cause skin irritation and the general toxicity of the isoindoline structure. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a building block in the synthesis of agrochemicals and pharmaceuticals, where the substituted isoindoline structure provides essential binding affinity to target enzymes. In medicinal chemistry, it has been employed in developing antimicrobial agents targeting bacterial and fungal pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The isoindoline-dione structure has also been explored in materials science for developing fluorescent probes, leveraging the electron-deficient isoindoline core to tune optical properties. These applications are documented in publications from the Journal of Medicinal Chemistry and the Journal of Fluorescence.
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