Octahydro-1H-isoindole
$350.00
CAS No.: 21850-12-4
Catalog No.: 196239
Purity: 95%
MF: C8H15N
MW: 125.215
Storage: 2-8 degree Celsius
SMILES: C1NCC2CCCCC12
Catalog No.: 196239
Purity: 95%
MF: C8H15N
MW: 125.215
Storage: 2-8 degree Celsius
SMILES: C1NCC2CCCCC12
Octahydro-1H-isoindole; CAS No.: 21850-12-4; Octahydro-1H-isoindole. PROPERTIES: This compound features an Octahydro-1H-isoindole structure, representing a fully hydrogenated isoindole framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 129.2 g/mol (C8H13N). The melting point ranges between 50-55 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: Octahydro-1H-isoindole serves as a valuable intermediate in pharmaceutical and chemical synthesis. Its Octahydro-1H-isoindole structure enables participation in various reactions, including nucleophilic substitution at the isoindole ring and hydrogenation/dehydrogenation reactions. In medicinal chemistry, it is used to develop bioactive molecules targeting the central nervous system and inflammatory pathways. The fully hydrogenated isoindole ring provides increased metabolic stability compared to aromatic isoindoles. This compound also functions as a building block in the synthesis of complex carbohydrates and glycosides. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the Octahydro-1H-isoindole scaffold for improved biological activity and pharmacokinetic properties.
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