(Z)-2-(1,3,3-trimethylindolin-2-ylidene)acetaldehyde
$300.00
CAS No.: 84-83-3
Catalog No.: LT0035
Purity: 95%
MF: C13H15NO
MW: 201.269
Storage: 2-8 degree Celsius
SMILES: CN1\C(\C(C2=CC=CC=C12)(C)C)=C/C=O
Catalog No.: LT0035
Purity: 95%
MF: C13H15NO
MW: 201.269
Storage: 2-8 degree Celsius
SMILES: CN1\C(\C(C2=CC=CC=C12)(C)C)=C/C=O
CAS NO.: 84-83-3;(Z)-2-(1,3,3-trimethylindolin-2-ylidene)acetaldehyde. PROPERTIES: This aldehyde-stilbene derivative presents as a pale yellow liquid with a molecular weight of approximately 223.3 g/mol. The (Z)-2-(1,3,3-trimethylindolin-2-ylidene)acetaldehyde combines an indoline framework with an aldehyde functionality in a conjugated system. It exhibits limited aqueous solubility but good dissolution in ethyl acetate and methanol. Stability characterization reveals sensitivity to oxidation and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The (Z)-2-(1,3,3-trimethylindolin-2-ylidene)acetaldehyde serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals (excluding agricultural applications). Its conjugated aldehyde system provides opportunities for Wittig and Horner-Wadsworth-Emmons reactions. Research teams utilize this compound as a starting material for creating kinase inhibitors and fluorescent probes. The indoline framework undergoes oxidation to form more complex ring systems. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity.
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