4,6-dichloroindoline-2,3-dione
$400.00
CAS No.: 18711-15-4
Catalog No.: 196228
Purity: 95%
MF: C8H3Cl2NO2
MW: 216.023
Storage: 2-8 degree Celsius
SMILES: ClC1=C2C(C(NC2=CC(=C1)Cl)=O)=O
Catalog No.: 196228
Purity: 95%
MF: C8H3Cl2NO2
MW: 216.023
Storage: 2-8 degree Celsius
SMILES: ClC1=C2C(C(NC2=CC(=C1)Cl)=O)=O
4,6-dichloroindoline-2,3-dione; CAS No.: 18711-15-4; 4,6-dichloroindoline-2,3-dione. PROPERTIES: This compound features a 4,6-dichloroindoline-2,3-dione structure, combining two chloro substituents and an indoline-2,3-dione framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 219.0 g/mol (C8H4Cl2NO2). The melting point ranges between 200-205 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 4,6-Dichloroindoline-2,3-dione serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 4,6-dichloroindoline-2,3-dione structure allows for participation in various reactions, including nucleophilic substitution at the chloro positions and electrophilic substitution at the indoline ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The dichloro substituents provide diverse substitution patterns for creating structural analogs. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel dichloroindoline derivatives based on the 4,6-dichloroindoline-2,3-dione scaffold.
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