methyl 6-methyl-1H-indole-5-carboxylate
$450.00
CAS No.: 672293-36-6
Catalog No.: 192681
Purity: 95%
MF: C11H11NO2
MW: 189.214
Storage: 2-8 degree Celsius
SMILES: CC1=C(C=C2C=CNC2=C1)C(=O)OC
Catalog No.: 192681
Purity: 95%
MF: C11H11NO2
MW: 189.214
Storage: 2-8 degree Celsius
SMILES: CC1=C(C=C2C=CNC2=C1)C(=O)OC
methyl 6-methyl-1H-indole-5-carboxylate; CAS No.: 672293-36-6; methyl 6-methyl-1H-indole-5-carboxylate. PROPERTIES: This methylated indole ester has molecular formula C10H9NO2. It typically appears as a pale yellow crystalline powder. The methyl 6-methyl-1H-indole-5-carboxylate demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its melting point ranges between 100-103 C, and it has a molecular weight of approximately 179.18 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may hydrolyze to the corresponding carboxylic acid upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The methyl 6-methyl-1H-indole-5-carboxylate functions as a valuable intermediate in the synthesis of 5-HT2C receptor agonists for obesity treatment where the ester group provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The methyl group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound serves as a building block in the preparation of liquid crystal materials with specific elastic constants, useful in display technologies with response times below 20 milliseconds as described in materials chemistry journals. The ester group can be further functionalized through hydrolysis or transesterification reactions to produce various derivatives for chemical research applications.
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