7-methyl-1H-indol-4-ol
$413.00
CAS No.: 19499-91-3
Catalog No.: 192675
Purity: 95%
MF: C9H9NO
MW: 147.177
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=2C=CNC12)O
Catalog No.: 192675
Purity: 95%
MF: C9H9NO
MW: 147.177
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=2C=CNC12)O
7-methyl-1H-indol-4-ol; CAS No.: 19499-91-3; 7-methyl-1H-indol-4-ol. PROPERTIES: This methylated indole phenol has molecular formula C9H8N2O. It generally appears as a white to slightly yellow crystalline powder. The 7-methyl-1H-indol-4-ol demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 130-133 C, and it has a molecular weight of approximately 156.17 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive products upon exposure to heat or shock. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 7-methyl-1H-indol-4-ol serves as a valuable intermediate in the synthesis of adenosine receptor antagonists for cardiovascular indications where the hydroxyl group provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The methyl group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound functions as a building block in the preparation of fluorescent dyes for bioimaging applications with excitation maxima around 360 nm and emission maxima around 430 nm, as described in bioanalytical chemistry journals. The hydroxyl group can be further functionalized through etherification or esterification reactions to produce various derivatives for chemical research applications.
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