7-bromo-3-iodo-1H-indole
$300.00
CAS No.: 793727-95-4
Catalog No.: 196851
Purity: 95%
MF: C8H5BrIN
MW: 321.943
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=C2C(=CNC12)I
Catalog No.: 196851
Purity: 95%
MF: C8H5BrIN
MW: 321.943
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC=C2C(=CNC12)I
7-bromo-3-iodo-1H-indole; CAS No.: 793727-95-4; 7-bromo-3-iodo-1H-indole. PROPERTIES: This bromo-iodo-substituted indole features molecular formula C?H?BrIN with molecular weight 298.94 g/mol. It typically exists as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 110-115 C. Exhibits IR absorption for C-Br (~600-500 cm??) and C-I (~550-450 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a bromo-iodo-substituted indole, 7-bromo-3-iodo-1H-indole is predominantly utilized in the synthesis of indole-based antitubercular agents. It serves as a key intermediate in constructing the core indole framework of these compounds, where the bromo and iodo substituents provide valuable sites for further functionalization as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its indole framework enables conjugation to fluorophores with enhanced photostability (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the bromo and iodo substituents contribute to improved flame retardancy and mechanical properties (Polymer International).
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