2-chloro-1-(4-methoxy-1H-indol-3-yl)ethan-1-one
$200.00
CAS No.: 858752-72-4
Catalog No.: 196831
Purity: 95%
MF: C11H10ClNO2
MW: 223.659
Storage: 2-8 degree Celsius
SMILES: ClCC(=O)C1=CNC2=CC=CC(=C12)OC
Catalog No.: 196831
Purity: 95%
MF: C11H10ClNO2
MW: 223.659
Storage: 2-8 degree Celsius
SMILES: ClCC(=O)C1=CNC2=CC=CC(=C12)OC
2-chloro-1-(4-methoxy-1H-indol-3-yl)ethan-1-one; CAS No.: 858752-72-4; 2-chloro-1-(4-methoxy-1H-indol-3-yl)ethan-1-one. PROPERTIES: This chlorinated indole ketone features molecular formula C??H?ClNO? with molecular weight 212.64 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like ethyl acetate and dichloromethane. Melting point approximately 100-105 C. Exhibits IR absorption for ketone (~1700 cm??) and C-Cl groups (~600-500 cm??). Thermogravimetric analysis reveals weight loss onset above 150 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chlorinated indole ketone, 2-chloro-1-(4-methoxy-1H-indol-3-yl)ethan-1-one is predominantly utilized in the synthesis of indole alkaloids. It serves as a key intermediate in constructing the core indole framework of these compounds, where the chloro substituent provides valuable sites for further functionalization as demonstrated in medicinal chemistry research (Journal of Natural Products). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its ketone functionality enables conjugation to biomolecules via oxime formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the indole group contributes to improved flame retardancy and mechanical properties (Polymer International).
Reviews
Write Your Own Review