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6-(trifluoromethyl)-1H-indazol-5-amine; CAS No.: 1000373-75-0; 6-(trifluoromethyl)-1H-indazol-5-amine. PROPERTIES: This compound is a 6-(trifluoromethyl)-1H-indazol-5-amine appearing as white crystalline powder. Its molecular weight is approximately 211.13 g/mol. It has melting point around 120-125 C. The compound is moderately soluble in polar organic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 25 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 6-(trifluoromethyl)-1H-indazol-5-amine is utilized in pharmaceutical research as indazole building block containing trifluoromethyl group as described in Journal of Medicinal Chemistry. It's employed in synthesis of certain antidepressant compounds mentioned in European Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for preparing trifluoromethyl-containing pharmaceuticals reported in Organic Process Research & Development. The trifluoromethyl group provides valuable electron-withdrawing effect beneficial in drug design applications.