4-bromo-6-methyl-1H-indazole
$300.00
CAS No.: 885521-94-8
Catalog No.: 111069
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: CC1=CC2=C(C=NN2)C(Br)=C1
Catalog No.: 111069
Purity: 95%
MF: C8H7BrN2
MW: 211.062
Storage: 2-8 degree Celsius
SMILES: CC1=CC2=C(C=NN2)C(Br)=C1
4-bromo-6-methyl-1H-indazole; CAS No.: 885521-94-8; ChemShuttle supplies methyl-substituted building blocks like 4-bromo-6-methyl-1H-indazole for allosteric modulator development. The methyl group at position 6 creates steric hindrance to direct coupling reactions to the 4-bromo position. This compound's molecular weight of 225.08 and calculated LogP of 2.7 enhance its utility in lead optimization phases. Our chemical synthesis companies developed a novel methylation protocol using dimethylzinc to achieve >95% regioselectivity. The methyl group improves metabolic stability by blocking oxidation sites while maintaining favorable solubility. We offer custom deuteration of the methyl group for ADME studies and metabolite identification. Technical support includes computed electrostatic potential maps and suggested synthetic pathways for derivatives.
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