3-chloro-1H-indazole-6-carboxylic acid
$437.00
CAS No.: 1086391-21-0
Catalog No.: 195536
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: ClC1=NNC2=CC(=CC=C12)C(=O)O
Catalog No.: 195536
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: ClC1=NNC2=CC(=CC=C12)C(=O)O
3-chloro-1H-indazole-6-carboxylic acid; CAS No.: 1086391-21-0; 3-chloro-1H-indazole-6-carboxylic acid. PROPERTIES: 3-chloro-1H-indazole-6-carboxylic acid presents as a white crystalline powder with molecular formula C9H5ClN2O2. It demonstrates a melting point around 220-223 C and exhibits good thermal stability. The compound shows fair solubility in warm aqueous sodium hydroxide solution and limited solubility in organic solvents. Proper storage requires keeping it in tightly sealed containers at room temperature. Safety considerations include avoiding ingestion and using appropriate first aid measures if eye contact occurs, as the carboxylic acid group may cause irritation. APPLICATIONS: This chlorinated indazole derivative is employed in the development of protease inhibitors for HIV therapy, where the 3-chloro-1H-indazole-6-carboxylic acid moiety contributes to active site coordination (Journal of Medicinal Chemistry). In agrochemical research, the compound serves as a lead structure for developing herbicides targeting dicot plants through inhibition of specific enzyme systems (Pest Management Science). Furthermore, its acidic functionality enables formation of pharmaceutically acceptable salts used in drug delivery systems to improve bioavailability (International Journal of Pharmaceutics).
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