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2,3-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole; CAS No.: 1310383-43-7; This 2,3-dimethyl-4-boronic indazole derivative serves as building blocks for BTK inhibitor development. The dimethyl groups block metabolic hotspots while the boronic acid enables PROTAC conjugation. Our custom chemical synthesis companies employ cryogenic lithiation-borylation to achieve regioselective functionalization of sensitive indazoles.