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1H-indazole-3,6-dicarboxylic acid, 6-methyl ester

$300.00
CAS No.: 885522-60-1
Catalog No.: 111071
Purity: 95%
MF: C10H8N2O4
MW: 220.184
Storage: 2-8 degree Celsius
SMILES: COC(=O)C1=CC2=C(C=C1)C(=NN2)C(O)=O
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111071
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1H-indazole-3,6-dicarboxylic acid, 6-methyl ester; CAS No.: 885522-60-1; ChemShuttle offers dicarboxylic acid derivatives like 1H-indazole-3,6-dicarboxylic acid 6-methyl ester for prodrug development. This bifunctional compound combines ester-protected acid at position 6 with free acid at position 3, enabling selective derivatization. The methyl ester enhances cell permeability while the free acid allows salt formation for improved solubility. Our chemical synthesis expertise ensures precise control over esterification selectivity in polyfunctional systems. The compound's calculated pKa values (3.1 and 4.7) inform formulation strategies for oral delivery. We provide custom hydrolysis studies under physiological conditions and support salt formation with various counterions. Technical documents include pH-solubility profiles and solid-state stability data.

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