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2-methyl-imidazo[1,2-a]pyridin-8-ol
$200.00
CAS No.: 79707-11-2
Catalog No.: 111055
Purity: 95%
MF: C8H8N2O
MW: 148.165
Storage: 2-8 degree Celsius
SMILES: CC1=CN2C=CC=C(O)C2=N1
Catalog No.: 111055
Purity: 95%
MF: C8H8N2O
MW: 148.165
Storage: 2-8 degree Celsius
SMILES: CC1=CN2C=CC=C(O)C2=N1
2-methyl-imidazo[1,2-a]pyridin-8-ol; CAS No.: 79707-11-2; ChemShuttle delivers novel cycle compounds like 2-methyl-imidazo[1,2-a]pyridin-8-ol, a privileged scaffold in antiviral research. This hydroxylated imidazopyridine exhibits strong hydrogen bonding capacity through its phenolic -OH group (pKa ~8.2) while maintaining membrane permeability. The methyl group at position 2 enhances steric protection against metabolic oxidation. Our chemical synthesis company developed a proprietary cyclization method using microwave-assisted synthesis to improve yield (83% vs traditional 55%). This building block is particularly valuable for RNA virus target engagement studies due to its planar aromatic system. We offer parallel synthesis services to generate focused libraries through O-alkylation or C-3 functionalization of the core structure.
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