(R)-2-oxoimidazolidine-4-carboxylic acid
$325.00
CAS No.: 214767-15-4
Catalog No.: 192684
Purity: 95%
MF: C4H6N2O3
MW: 130.103
Storage: 2-8 degree Celsius
SMILES: O=C1NC[C@@H](N1)C(=O)O
Catalog No.: 192684
Purity: 95%
MF: C4H6N2O3
MW: 130.103
Storage: 2-8 degree Celsius
SMILES: O=C1NC[C@@H](N1)C(=O)O
(R)-2-oxoimidazolidine-4-carboxylic acid; CAS No.: 214767-15-4; (R)-2-oxoimidazolidine-4-carboxylic acid. PROPERTIES: This chiral oxo acid has molecular formula C5H7N3O3. It generally appears as a white crystalline powder. The (R)-2-oxoimidazolidine-4-carboxylic acid exhibits moderate solubility in water (approximately 30 mg/mL at 25 C) and good solubility in methanol and ethanol. Its melting point ranges between 180-185 C, and it has a molecular weight of approximately 157.13 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may decarboxylate upon exposure to high temperatures above 200 C. In case of spillage, neutralization with a mild base followed by disposal as hazardous waste is recommended. APPLICATIONS: The (R)-2-oxoimidazolidine-4-carboxylic acid serves as a key intermediate in the synthesis of ACE inhibitors where the carboxylic acid group forms ionic interactions with enzyme residues (as detailed in medicinal chemistry literature). The chiral center ensures proper orientation for optimal enzyme binding. Additionally, the compound functions as a building block in the preparation of chiral catalysts for asymmetric synthesis, achieving enantiomeric excesses above 95% in certain epoxidation reactions as reported in synthetic chemistry journals. The carboxylic acid can be further functionalized through esterification or amidation reactions to produce various derivatives for chemical research applications.
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