2-amino-5,6-dichlorobenzimidazole
$360.00
CAS No.: 18672-03-2
Catalog No.: 194960
Purity: 95%
MF: C7H5Cl2N3
MW: 202.044
Storage: 2-8 degree Celsius
SMILES: NC=1NC2=C(N1)C=C(C(=C2)Cl)Cl
Catalog No.: 194960
Purity: 95%
MF: C7H5Cl2N3
MW: 202.044
Storage: 2-8 degree Celsius
SMILES: NC=1NC2=C(N1)C=C(C(=C2)Cl)Cl
2-amino-5,6-dichlorobenzimidazole; CAS No.: 18672-03-2; 2-amino-5,6-dichlorobenzimidazole. PROPERTIES: 2-amino-5,6-dichlorobenzimidazole is a crystalline solid with molecular formula C7H5Cl2N3. It has a melting point of approximately 215 C and is moderately soluble in organic solvents like DMSO and DMF but sparingly soluble in water. The compound is heat sensitive and degrades upon prolonged exposure to light and moisture. Proper storage requires a tightly sealed container in a cool, dark place at temperatures below 20 C. From a safety perspective, this benzimidazole derivative poses moderate acute toxicity via inhalation and skin contact. It may cause eye irritation and skin sensitization. Chronic exposure could potentially affect the central nervous system based on structurally similar compounds. Always use in well-ventilated areas with appropriate personal protective equipment including N95 masks, nitrile gloves, and safety goggles. APPLICATIONS: In pharmaceutical research, 2-amino-5,6-dichlorobenzimidazole serves as a valuable intermediate for synthesizing antiviral agents targeting RNA viruses. Its benzimidazole scaffold provides a foundation for developing compounds with selective inhibition against viral polymerases (Journal of Medicinal Chemistry). Additionally, this compound finds application in agrochemical formulations as a precursor for fungicides that disrupt fungal cell membrane integrity. The chlorinated benzimidazole structure confers enhanced stability in environmental conditions, making it suitable for protective coatings in industrial applications where antimicrobial properties are required (Pesticide Science). The amino functionality allows for further derivatization to introduce targeting moieties for specific biological systems.
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