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furo[2,3-b]pyridin-5-amine; CAS No.: 34668-30-9; Furo[2,3-b]pyridin-5-amine from our heterocycles collection combines oxygen and nitrogen heteroatoms in a bicyclic system ideal for H-bond donor/acceptor optimization. The 5-amino group permits direct functionalization via Buchwald-Hartwig couplings. As a chemical synthesis company, we employ continuous flow chemistry for safe handling of pyrophoric reagents in furan ring formation. This compound's balanced lipophilicity makes it valuable for blood-brain barrier penetration studies. We provide custom N-protected derivatives to facilitate parallel synthesis approaches in lead optimization.