5-(3-chlorophenyl)furan-2-carbaldehyde; CAS No.: 22078-59-7; 5-(3-chlorophenyl)furan-2-carbaldehyde. PROPERTIES: 5-(3-chlorophenyl)furan-2-carbaldehyde is a crystalline solid. Its molecular formula is C11H7ClO2, and the molecular weight is approximately 206.63 g/mol. The compound has a melting point of approximately 70-72 C. It is moderately soluble in common organic solvents such as dichloromethane and ethyl acetate, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a furan ring, a chloro group, and an aldehyde group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 5-(3-chlorophenyl)furan-2-carbaldehyde serves as a versatile intermediate. The aldehyde group can undergo various reactions such as nucleophilic addition, oxidation, and condensation. The chloro group provides a site for substitution reactions. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For instance, in the development of certain anticancer drugs, the structure of 5-(3-chlorophenyl)furan-2-carbaldehyde can be modified to enhance the drug's ability to target cancer cells and improve its therapeutic index (as described in medicinal chemistry research articles). Additionally, in the field of materials science, it can be incorporated into the synthesis of functional materials such as organic semiconductors or photovoltaic materials, where its structure can affect the material's electronic and optical properties (as mentioned in materials chemistry research papers).