4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one
$200.00
CAS No.: 91526-18-0
Catalog No.: LT0244
Purity: 95%
MF: C5H6O4
MW: 130.099
Storage: 2-8 degree Celsius
SMILES: OCC=1OC(OC1C)=O
Catalog No.: LT0244
Purity: 95%
MF: C5H6O4
MW: 130.099
Storage: 2-8 degree Celsius
SMILES: OCC=1OC(OC1C)=O
CAS NO.: 91526-18-0;4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one. PROPERTIES: This hydroxymethyl dioxolone presents as a white crystalline solid with a molecular weight of approximately 142.1 g/mol. The 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one combines a hydroxymethyl group with a methyl-substituted dioxolone ring. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one serves as a key intermediate in the synthesis of various pharmaceuticals. Its dioxolone framework provides opportunities for constructing antiviral agents and metalloenzyme inhibitors. Research teams utilize this compound as a starting material for creating neuraminidase inhibitors and matrix metalloproteinase inhibitors. The hydroxymethyl group enhances water solubility compared to non-hydroxy analogs. Additionally, it serves as a building block for creating chiral auxiliaries for asymmetric synthesis and fluorescent probes for bioimaging applications.
Reviews
Write Your Own Review