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CAS NO.: 144689-94-1;diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate. PROPERTIES: This diethyl imidazole dicarboxylate presents as a colorless liquid with a molecular weight of approximately 266.3 g/mol. The diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate combines a propylimidazole framework with two ethyl ester groups. It exhibits limited aqueous solubility but good dissolution in ethyl acetate and methanol. Stability characterization reveals sensitivity to base-catalyzed hydrolysis of the ester groups and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate serves as a key intermediate in the synthesis of various pharmaceuticals. Its imidazole framework provides opportunities for constructing antifungal agents and H+/K+ ATPase inhibitors. Research teams utilize this compound as a starting material for creating proton pump inhibitors and antifungal drugs. The diethyl ester groups undergo hydrolysis to carboxylic acids or reduction to alcohols for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.