6,7-dihydro-2H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3(5H)-one
$275.00
CAS No.: 25823-52-3
Catalog No.: LT0090
Purity: 95%
MF: C13H12N2O
MW: 212.252
Storage: 2-8 degree Celsius
SMILES: N=1NC(C=C2C1C1=C(CCC2)C=CC=C1)=O
Catalog No.: LT0090
Purity: 95%
MF: C13H12N2O
MW: 212.252
Storage: 2-8 degree Celsius
SMILES: N=1NC(C=C2C1C1=C(CCC2)C=CC=C1)=O
CAS NO.: 25823-52-3;6,7-dihydro-2H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3(5H)-one. PROPERTIES: This complex heterocycle presents as a white crystalline solid with a molecular weight of approximately 258.3 g/mol. The 6,7-dihydro-2H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3(5H)-one combines fused benzene and cyclohepta rings with a pyridazine core, exhibiting limited aqueous solubility but good dissolution in DMSO and DMF. Stability testing reveals sensitivity to acid-catalyzed ring-opening and base-promoted tautomerism, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 6,7-dihydro-2H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3(5H)-one serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique fused ring system provides opportunities for constructing complex alkaloids and receptor-targeted molecules. Research teams utilize this compound as a starting material for creating kinase inhibitors and serotonin-norepinephrine reuptake inhibitors. The ketone functionality undergoes reduction to secondary alcohols or condensation reactions for further functionalization. Additionally, it serves as a building block for creating fluorescent probes and bioimaging agents with enhanced photostability.
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