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CAS NO.: 72898-13-6; 2,3,4,9-Tetrahydro-1H-carbazol-2-amine hydrochloride. PROPERTIES: 2,3,4,9-Tetrahydro-1H-carbazol-2-amine hydrochloride is the hydrochloride salt form of the corresponding amine. It is highly soluble in water due to its ionic nature and has better solubility in polar solvents compared to the free base. It appears as a white to off-white crystalline powder. Storage should be in a tightly closed container in a dry place, protected from light. When handling, care should be taken to avoid inhalation of dust, as it may cause respiratory irritation. APPLICATIONS: Similar to its free base form, this hydrochloride salt is valuable in drug development. The enhanced solubility of the salt form can be beneficial for formulating drug candidates, especially for in vitro assays and preclinical studies. It can be further modified chemically to create derivatives with improved pharmacological properties, such as increased potency or selectivity. Its use in the pharmaceutical research and development process is based on the need for compounds with favorable physicochemical properties for drug formulation, as described in pharmaceutical science literature.