(1H-benzo[d][1,2,3]triazol-1-yl)(4-nitrophenyl)methanone
$400.00
CAS No.: 4231-71-4
Catalog No.: 197505
Purity: 95%
MF: C13H8N4O3
MW: 268.232
Storage: 2-8 degree Celsius
SMILES: N1(N=NC2=C1C=CC=C2)C(=O)C2=CC=C(C=C2)[N+](=O)[O-]
Catalog No.: 197505
Purity: 95%
MF: C13H8N4O3
MW: 268.232
Storage: 2-8 degree Celsius
SMILES: N1(N=NC2=C1C=CC=C2)C(=O)C2=CC=C(C=C2)[N+](=O)[O-]
(1H-benzo[d][1,2,3]triazol-1-yl)(4-nitrophenyl)methanone; CAS No.: 4231-71-4; (1H-benzo[d][1,2,3]triazol-1-yl)(4-nitrophenyl)methanone. PROPERTIES: This nitro-substituted triazolone features molecular formula C??H?N?O? with molecular weight 263.24 g/mol. It generally appears as a white crystalline powder. Soluble in non-polar and slightly polar organic solvents like hexanes and ethyl acetate. Melting point approximately 130-135 C. Exhibits IR absorption for ester (~1750 cm??) and nitro groups (~1520 and ~1350 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a nitro-substituted triazolone, (1H-benzo[d][1,2,3]triazol-1-yl)(4-nitrophenyl)methanone is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the triazole and nitro groups provide valuable binding affinity for the kinase active site as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its nitro group enhances solubility and binding affinity for target biomolecules (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the triazole group contributes to improved flame retardancy and mechanical properties (Polymer International).
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