![tert-butyl (3-cyano-7-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophen-2-yl)carbamate](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/x/h/xh1500.jpg)
![2-methylbenzo[b]thiophene](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/w/l/wlz2761_1.jpg)
3-chlorobenzo[b]thiophene-2-carbonyl chloride
$320.00
CAS No.: 21815-91-8
Catalog No.: WLZ1712
Purity: 95%
MF: C9H4Cl2OS
MW: 231.103
Storage: 2-8 degree Celsius
SMILES: O=C(Cl)C1=C(Cl)C2=CC=CC=C2S1
Catalog No.: WLZ1712
Purity: 95%
MF: C9H4Cl2OS
MW: 231.103
Storage: 2-8 degree Celsius
SMILES: O=C(Cl)C1=C(Cl)C2=CC=CC=C2S1
CAS NO.: 21815-91-8; 3-chlorobenzo[b]thiophene-2-carbonyl chloride. PROPERTIES: This halogenated aromatic acyl chloride features a chlorine atom on a benzo[b]thiophene ring connected to an acyl chloride group, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The 3-chlorobenzo[b]thiophene-2-carbonyl chloride typically appears as a white to off-white crystalline solid with moderate solubility in common organic solvents. Its molecular structure includes an electron-withdrawing acyl chloride group and a chlorine atom that influence the electronic properties of the aromatic system. For optimal stability and to prevent premature reactions, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves and safety goggles are recommended. This compound is sensitive to light and moisture, requiring careful environmental control during storage and use. In case of skin contact, wash thoroughly with soap and water; if eye contact occurs, rinse immediately and seek medical evaluation. APPLICATIONS: The 3-chlorobenzo[b]thiophene-2-carbonyl chloride serves as a versatile building block in organic synthesis, particularly for creating acylated bioactive molecules. The acyl chloride group provides a handle for nucleophilic acyl substitution reactions, enabling the creation of amides, esters, and other derivatives. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The chlorine substituent contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound can benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.
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