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6-bromo-2-methylbenzo[d]thiazole
$300.00
CAS No.: 5304-21-2
Catalog No.: 196161
Purity: 95%
MF: C8H6BrNS
MW: 228.114
Storage: 2-8 degree Celsius
SMILES: BrC1=CC2=C(N=C(S2)C)C=C1
Catalog No.: 196161
Purity: 95%
MF: C8H6BrNS
MW: 228.114
Storage: 2-8 degree Celsius
SMILES: BrC1=CC2=C(N=C(S2)C)C=C1
6-bromo-2-methylbenzo[d]thiazole; CAS No.: 5304-21-2; 6-bromo-2-methylbenzo[d]thiazole. PROPERTIES: This compound features a 6-bromo-2-methylbenzo[d]thiazole structure, incorporating a bromine atom and a methyl group on the benzo[d]thiazole framework. It typically appears as a white to pale yellow crystalline solid with a molecular weight of approximately 242.0 g/mol (C9H6BrNS). The melting point ranges between 105-110 C, and it exhibits moderate solubility in common organic solvents like DMSO, DMF, and dichloromethane while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include using appropriate personal protective equipment. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 6-Bromo-2-methylbenzo[d]thiazole serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 6-bromo-2-methylbenzo[d]thiazole structure allows for cross-coupling reactions at the bromine position, enabling the introduction of various aryl and vinyl substituents. In medicinal chemistry, it is used to develop biologically active compounds, particularly those targeting G protein-coupled receptors and kinases. The bromine atom can be displaced in nucleophilic substitution reactions to introduce amine or alcohol groups. This compound also functions as a building block in the synthesis of fluorescent dyes, where the benzo[d]thiazole moiety contributes to fluorescence properties. Academic research employs it as a starting material for synthesizing novel heterocycles in Organic Chemistry journals, focusing on the development of bioactive molecules based on the 6-bromo-2-methylbenzo[d]thiazole scaffold.
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