6-fluorochroman-4-amine
$350.00
CAS No.: 238764-22-2
Catalog No.: 111280
Purity: 95%
MF: C9H10FNO
MW: 167.183
Storage: 2-8 degree Celsius
SMILES: NC1CCOC2=C1C=C(F)C=C2
Catalog No.: 111280
Purity: 95%
MF: C9H10FNO
MW: 167.183
Storage: 2-8 degree Celsius
SMILES: NC1CCOC2=C1C=C(F)C=C2
6-fluorochroman-4-amine; CAS No.: 238764-22-2; ChemShuttle specializes in fluorinated building blocks like 6-fluorochroman-4-amine for kinase inhibitor development. This chiral amine combines fluorinated aromatic properties with hydrogen bonding capacity through its primary amine group. With molecular weight 167.17 and calculated LogD7.4 1.1, it demonstrates optimal balance between blood-brain barrier penetration and aqueous solubility. As a worldwide chemical supplier, we employ asymmetric hydrogenation techniques to achieve >99% enantiomeric purity. The fluorine atom enhances metabolic stability while the chroman system provides -stacking capabilities for target engagement. Our small molecule synthesis services include custom protection strategies for the amine group and scale-up to kilogram quantities with comprehensive stability data under ICH conditions.
Reviews
Write Your Own Review