![3-methylbenzo[d]isoxazol-6-ol](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/9/196169_2.jpg)
5-fluorobenzo[d]isoxazol-3-amine
$250.00
CAS No.: 868271-13-0
Catalog No.: 196175
Purity: 95%
MF: C7H5FN2O
MW: 152.128
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC2=C(C(=NO2)N)C1
Catalog No.: 196175
Purity: 95%
MF: C7H5FN2O
MW: 152.128
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC2=C(C(=NO2)N)C1
5-fluorobenzo[d]isoxazol-3-amine; CAS No.: 868271-13-0; 5-fluorobenzo[d]isoxazol-3-amine. PROPERTIES: This compound presents a 5-fluorobenzo[d]isoxazol-3-amine structure, combining an amino group, a fluorine atom, and a benzo[d]isoxazole ring system. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 175.1 g/mol (C8H6FN3O). The melting point ranges between 145-150 C, and it exhibits moderate solubility in common organic solvents like ethanol and methanol while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing gloves, eye protection, and a lab coat. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 5-Fluorobenzo[d]isoxazol-3-amine is employed in pharmaceutical research as a lead compound. Its 5-fluorobenzo[d]isoxazol-3-amine structure enables diverse substitution patterns, making it suitable for developing enzyme inhibitors and receptor modulators. The amino group can undergo acylation, sulfonation, or coupling reactions to introduce various substituents. In medicinal chemistry, it is used to create bioactive molecules targeting the central nervous system and inflammatory pathways. The fluorine atom provides metabolic stability and favorable binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent probes for bioimaging applications, where the benzo[d]isoxazole moiety contributes to fluorescence properties. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the 5-fluorobenzo[d]isoxazol-3-amine scaffold for improved biological activity and selectivity.
Reviews
Write Your Own Review