benzofuran-5-carboxylic acid
$250.00
CAS No.: 90721-27-0
Catalog No.: 195066
Purity: 95%
MF: C9H6O3
MW: 162.144
Storage: 2-8 degree Celsius
SMILES: O1C=CC2=C1C=CC(=C2)C(=O)O
Catalog No.: 195066
Purity: 95%
MF: C9H6O3
MW: 162.144
Storage: 2-8 degree Celsius
SMILES: O1C=CC2=C1C=CC(=C2)C(=O)O
benzofuran-5-carboxylic acid; CAS No.: 90721-27-0; benzofuran-5-carboxylic acid. PROPERTIES: Benzofuran-5-carboxylic acid appears as a white to off-white crystalline powder with a slight acidic odor. Its molecular formula is C9H6O3, corresponding to a molecular weight of approximately 174.14 g/mol. The compound exhibits a melting point in the range of 180-183 C and demonstrates moderate solubility in hot water and common organic solvents such as methanol and dimethylformamide. It is stable under normal laboratory conditions but should be protected from prolonged exposure to moisture and heat. Proper storage involves keeping it in a tightly sealed container at room temperature (15-25 C) in a dry environment. Safety considerations include wearing appropriate protective equipment as the compound may cause skin and eye irritation. Inhalation of dust should be avoided, and in case of accidental exposure, thorough washing with water and medical consultation is advised. APPLICATIONS: Benzofuran-5-carboxylic acid serves as a versatile intermediate in the synthesis of pharmaceuticals, particularly in the preparation of certain anticancer agents and anti-inflammatory drugs where its carboxylic acid and benzofuran groups provide opportunities for further functionalization and bioactive molecule design (Journal of Medicinal Chemistry). In materials science, benzofuran-5-carboxylic acid functions as a building block for creating liquid crystal polymers and electro-optical materials, where its rigid aromatic structure and flexible carboxylic acid group enable desired mesomorphic properties and optical anisotropy (Journal of Polymer Science). Additionally, it finds application in the preparation of UV-absorbing coatings and photostabilizers, where its molecular framework provides effective light absorption and energy dissipation capabilities (Progress in Organic Coatings). The compound is also employed in organic synthesis as a starting material for the preparation of chiral building blocks through asymmetric transformations, enabling the synthesis of complex molecules with high stereochemical control (Tetrahedron Letters).
Reviews
Write Your Own Review