2,3-dihydrobenzofuran-4-amine hydrochloride
$500.00
CAS No.: 2135331-32-5
Catalog No.: 192607
Purity: 95%
MF: C8H10ClNO
MW: 171.627
Storage: 2-8 degree Celsius
SMILES: Cl.O1CCC=2C1=CC=CC2N
Catalog No.: 192607
Purity: 95%
MF: C8H10ClNO
MW: 171.627
Storage: 2-8 degree Celsius
SMILES: Cl.O1CCC=2C1=CC=CC2N
2,3-dihydrobenzofuran-4-amine hydrochloride; CAS No.: 2135331-32-5; 2,3-dihydrobenzofuran-4-amine hydrochloride. PROPERTIES: 2,3-dihydrobenzofuran-4-amine hydrochloride is a white crystalline powder with a molecular weight of 207.69 g/mol. It has a melting point between 200-205 C (hydrochloride salt) and is freely soluble in water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety precautions include avoiding ingestion and skin contact, as it may cause gastrointestinal discomfort and dermal irritation. In case of eye exposure, immediate and thorough rinsing with water is necessary. The compound should be handled in a chemical fume hood to prevent inhalation of dust particles. APPLICATIONS: 2,3-dihydrobenzofuran-4-amine hydrochloride is primarily used in pharmaceutical development as a prodrug intermediate. The dihydrobenzofuran ring system allows for controlled release of the active amine upon administration, as described in drug delivery systems literature. In oncology research, it serves as a building block for creating kinase inhibitors where the benzofuran scaffold enhances kinase domain binding, as reported in medicinal chemistry studies. Additionally, it is utilized in agrochemical formulations as a precursor for creating fungicides targeting fungal kinase pathways, where the benzofuran ring system interacts with fungal enzymes, as detailed in pesticide chemistry publications. The compound also finds application in materials science as a monomer for creating electroactive polymers, where the benzofuran structure contributes to charge transport properties, as outlined in organic electronics research. Furthermore, it is employed in analytical chemistry as a chiral resolving agent for separating enantiomers of pharmaceutical compounds, where the benzofuran framework forms diastereomeric complexes with racemic mixtures, as described in separation science literature. Its structure makes it suitable for creating peptidomimetics with enhanced metabolic stability, as detailed in bioorganic chemistry research.
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